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A Meta-Analysis of the Ventilator Circuit Change Period on Ventilator-Associated Pneumonia

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KMID : 1004620100160030111
¼ÛÁÖÇö ( Song Ju-Hyun ) - Áß¾Ó´ëÇб³º´¿ø °£È£ºÎ

±è°æÈñ ( Kim Kyung-Hee ) - Áß¾Ó´ëÇб³ °£È£Çаú

Abstract

Purpose: This meta-analysis was aimed to investigate the evidence of proper period of the ventilator circuit change using existing research.

Methods: For this study, 14 published studies between 1995 and 2010 were tested by Macaskill, Funnel Plot, the Odds Ratio of DerSimonian and Laird, Fisher and Liptak analysis.

Results: There were no publication bias found in the subjects. The results of the meta-analysis demonstrated no statistically significant differences were observed in neither the Odds Ratio (OR=1.18, 95% CI=0.94-1.47) of the frequency of ventilator-associated pneumonia and the mortality based on the period of the ventilator circuit change (Fisher p=.332, Liptak p=.498), nor the ventilation duration of ventilator (Fisher p=.843, Liptak p=.506), and the hospital length of stay (Fisher p=.254, Liptak p=.480).

Conclusion: In order to present more concrete guidelines on the period of the ventilator circuit change, further research is warranted to thoroughly control confounding variables which related to the periods of the ventilator circuit change.
KeyWords
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Ventilator-associated pneumonia, Ventilator circuit, Ventilator circuit change period, Meta-analysis
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